One‐Pot Multicomponent Synthesis of Bis(diamino‐1,3,5‐triazines) under Microwave Irradiation

A new method for the synthesis of bis(1,3,5-triazine-2,4-diamines) was developed using a one-pot multicomponent approach. The performed acid-catalyzed reaction cyanoguanidine with amines and aldehydes, followed by dehydrogenative aromatization dihydrotriazine intermediates upon heating alkali. Two types were prepared either piperazine as bifunctional amine or terephthaldehyde aldehyde thus affording products p-phenylene link between two 1,3,5-triazine rings. microwave-assisted allows fast convenient diverse bis(1,3,5-triazine-2,4-diamines).